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ATRIAL FIBRILLATION


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Below is a short summary article on atrial fibrillation where you can learn more about it in easy to understand language. For more information Click on the link for more articles and information, including the newest news and treatments.

Summary
What is Atrial Fibrillation?
Symptoms of A-Fib
How A-Fib is Diagnosed
Medications
Invasive Treatments
Treatment for A-Fib
Prevention of A-Fib

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Summary

When the heart is not beating at a steady rate (usually between 60 and 100 times a minute), the irregular heartbeats are called arrhythmias. The most common type of sustained arrhythmia is atrial fibrillation, affecting about two million Americans every year. Atrial fibrillation got its name because the atria (the heart's upper chambers) send rapidly firing electrical signals that cause them to quiver, rather than contract normally. The result is an abnormally fast and highly irregular heartbeat.

In AF, since the upper chambers of the heart quiver instead of contracting, blood may pool in the atria and there is a risk of blood clots being formed. If a blood clot breaks off into the general circulation, this could cause a stroke. As a result, atrial fibrillation causes approximately 15 percent of all strokes, and is associated with both greater complications and greater risk of death from heart attacks in people over the age of 65. The risk of stroke in atrial fibrillation can be reduced by taking anticoagulants (medications that inhibit blood clotting).

Atrial fibrillation is associated with many different underlying heart conditions, such as heart failure or valvular heart disease. Many patients also experience atrial fibrillation in the absence of structural heart disease (“lone atrial fibrillation”), due to causes such as abnormal thyroid function or excessive alcohol use. If necessary, cardioversion may be used to bring the heartbeat back to normal by using either drugs or defibrillator paddles that deliver an electric shock to the patient's chest. However, although cardioversion may restore a normal rhythm, there is a risk that atrial fibrillation may happen again. Therefore, antiarrhythmics may be required to maintain a normal rhythm. Surgery or ablation may also be options in some cases. With treatment, many people are able to live normal, active lives.

What is atrial fibrillation?

Atrial fibrillation (AF) is a rapid, irregular heart rhythm (arrhythmia) caused by abnormal electrical signals from the upper chambers of the heart (atria). Electrical signals should normally be coming only from the sinus node (the heart's natural pacemaker) in a steady rhythm — about 60 to 100 beats per minute. AF is marked by rapidly firing signals that come from the atria, increasing the heart rate to 100 to 175 beats per minute or more. In response to these many rapid and chaotic signals, the atria quiver instead of contracting properly. Due to these abnormal contractions, the heart's lower chambers ventricles beat rapidly and irregularly.

Since the atria are quivering and not contracting normally, blood may pool in the atria, which can lead to formation of blood clots. If part of a clot breaks off and leaves the heart via the arteries, it can become lodged in blood vessels leading to the brain, lungs or other parts of the body. Depending upon where the traveling blood clot (embolus) becomes lodged, the patient could experience symptoms ranging from cold feet to a stroke.

AF is the most common type of sustained arrhythmia, affecting two million people each year in the United States alone. However, not all irregular heartbeats are a sign of AF. Skips, pauses or unusually strong/irregular heartbeats palpitations commonly occur in people with no history of heart problems. Some are related to more serious cardiac problems, and others are not. People who experience irregular heartbeats are encouraged to speak with their physician.

What are the symptoms of atrial fibrillation?

Many patients who experience AF are symptom-free and unaware of their abnormal rhythms. Other patients experience physical symptoms, including:

How is atrial fibrillation diagnosed?

Brief episodes of AF are known as transient atrial fibrillation. These episodes occur for a few minutes to a few hours at a time before the heart returns to a normal rhythm. Transient AF is harder to diagnose because it may or may not be detected by the patient. Chronic, constant cases of AF are easier to diagnose.

There are a variety of ways to diagnose AF. For example, the physician may use a stethoscope to listen for irregular heart rhythms. Additional tests that may be ordered include the following:

What is the treatment for atrial fibrillation?

As with any arrhythmia, treatment of AF will depend on the nature and severity of the irregular rhythm, as well as the nature of any underlying heart condition(s). Treating AF usually includes treating the underlying condition, such as high blood pressure or heart failure.

Medications that may be used include the following:

  • Beta blockers, calcium channel blockers and Digoxin. Medications that slow transmission of electrical impulses from the atria to the ventricles. This slows the overall heart rate during atrial fibrillation.
  • Anticoagulants. Medications that inhibit the formation of blood clots.
  • Antiarrhythmics. Medications that stabilize the heart rhythm, helping to maintain a normal rhythm. Prescribed medication (particularly anticoagulants and antiarrhythmics) must be monitored carefully to detect any side effects, which can include bleeding or increased/worsened arrhythmias. Patients on such medications are advised to become familiar with taking their own pulse, so that any irregular rhythm will be promptly discovered.

    More invasive treatments include the following:

    • Cardioversion returns AF to a normal heart rhythm through either an electric shock or drugs. Cardioversion does not work for all patients. Only those who can maintain normal sinus rhythm are approved for this procedure. In those patients, cardioversion has about an 80 to 95 percent success rate.
    • Ablation, through the use of radiofrequency energy, may be able to burn out (ablate) the tissues and pathways from which the faulty signals arise. Because ablation may sometimes diminish the heart's natural pacemaking abilities, an artificial pacemaker may be implanted to keep the heart beating at a regular pace and with a normal rhythm.
    • Implantable atrial defibrillators are still considered experimental. They are devices that function like pacemakers, delivering electrical impulses to keep the heart's rhythm on course over the long term. Because the shock they deliver can be strong and somewhat painful, they are best sited to those with intermittent, rather than chronic, AF.
    • In the Maze procedure, a surgeon carefully makes a number of small cuts in the atrial wall, thus designing a maze of new pathways through which electrical signals can travel. As the signals travel through this newly created maze instead of randomly leaping from various parts of the heart, AF is reduced. This is currently an open-heart surgery that requires the use of a heart-lung machine, but researchers are working to achieve the same goal with a catheter or other minimally invasive techniques.

    Can atrial fibrillation be prevented?

    Knowing the most common AF risk factors can help in preventing or recognizing symptoms. These risk factors include:

    • Age (about one percent of adults over 60 experience AF)
    • Coronary artery disease
    • Hypertension (high blood pressure)
    • Congenital heart disease
    • Thyroid disease
    • Inflammation of the heart lining (pericarditis)
    • Previous heart attack
    • Congestive heart failure
    • Chronic lung disease, such as asthma, or other pulmonary conditions that cause a shortage of oxygen in the blood such as chronic obstructive pulmonary disease (COPD)
    • Alcohol abuse
    • Illegal drug abuse (e.g., cocaine)
    • Excessive caffeine or decongestant use
    • Mitral valve dysfunction

    In rare cases (estimated at one in 10,000) young adults can experience AF without any risk factors or underlying heart disease. This is referred to as "lone atrial fibrillation" and is often associated with stress and/or the use of drugs or alcohol.

    People are encouraged to speak with their physician if they feel a flutter, skipped beat or any other unusual beat activity. Those who continue to experience symptoms of AF even after treatment are also urged to contact their physician immediately. Many AF patients are able to live normal, active lives.

     

     

     LINKS to Atrial Fibrillation Articles & Sites

    DOFETILIDE: A NEW CLASS III ANTIARRHYTHMIC FOR THE MANAGEMENT OF ATRIAL FIBRILLATION (2001)
    Learn how a new antiarrhythmic drug helps manage sustained atrial fibrillation. (From: Prog Cardiovasc Nurs 16(3):126-129, 2001)

    HEART CENTER ONLINE A complete center with atrial fibrillation information.

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    Last Modified on June 24, 2002